Trademarks: Avicel PH-102. 4. Report Category. Protect them from sunshine or rain. }[eD-1-8$#Yi^$o8Nc6vwfw;wBT~[Rgi1?%T*/J:/'+Gf'Ae*j@{Rh+2oN|Sbtt;z#v8})F#z=:*]q+U>+ .e ^Q-{@ RPC t/(If>8P&%wNPMJw,VI2aUqRqe3bC,a;C&4RQSf*(=I$r{'%jmk1LUZV(*is6r&wQPAAoID4p?,"lp:wE+)v(_w 'yelVnMh=gIYjK:9v{$G;b8=lGG1_,h^0F2`a~Kusz1p#NS*qt6,F:7+Rma-4u} DINFzJ"Mlctg*~HEge It is highly versatile and is therefore also widely used in topicals and semi-solid & liquid dosage forms, including ointments, creams, gels, pastes, solutions, suspensions, and emulsions. Kristensen, T. Schfer, P. Kleinebudde, Direct pelletization in a rotary processor controlled by torque measurements. However, if handling bulk powders, observance of appropriate safeguards is recommended. Performing this action will revert the following features to their default settings: Hooray! This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication Explore how we work and why we apply science and creativity for a better world to everything we do. It should be noted that native cellulose itself is completely indigestible, and its hydrolysis during the production of microcrystalline cellulose does not alter its behaviour in the intestine. Cellulose microcrystalline for column chromatography. Avicel is a brand name by Dupont for grades of Microcrystalline cellulose. Dyvo5bp#bR W7~IF C" d6zLz~!#>@HO}sx;hm>> POLYOX resins are nonionic polyethylene oxide solubility polymers. Are you looking for information about products and services by region? Magazine: Material safety data sheet - FMC Corporation. AVICEL RC 581. on Avicel microcrystalline cellulose, the most trusted excipient brand for decades. By producing Avicel . Alubra is also less susceptible to over-blending contributing to more flexible process conditions and reduced waste due to over blended batch failures. Solid dispersions are one of the key technologies for formulating oral solid dosage forms containing APIs with bioavailability challenges. 3 0 obj SUBSTANCE IDENTIFICATION 1.1. (1962). They are high molecular weight, highly sulfated, linear molecules with a galactose backbone. (Microcrystalline Cellulose Market Pr. %PDF-1.4 They are made up of sulfated and non-sulfated repeating units of galactose and 3,6-anhydrogalactose. Instead, they obtained a stable colloidal suspension. Home. In the late 1960s, Avicel Microcrystalline cellulose was registered in the supplement to the National Formulary as a pharmaceutical excipient. 3t;zAXa[j.7ZX[GL9e,>6sVV`T6`#W MATERIAL SAFETY DATA SHEET Avicel PC 611 Microcrystalline Cellulose Page 1 of 8 MSDS Ref. Microcrystalline cellulose was negative in the Ames mutagenicity assay [FMC Study Number I91-1189], and caused no : 5 This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication Standard, 29 CFR 1910.1200 and Canadas Workplace Hazardous Materials Information System (WHMIS) requirements. ]c\RbKSTQ C''Q6.6QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ p@" endstream Document(s): certificate data msds. PharmaCentral 2021 . 1.3. Alubra sodium stearyl fumarate from IFF Pharma Solutions is a comparatively hydrophilic lubricant widely used in capsule and tablet formulations. Avicel PH-200 microcrystalline cellulose NF, Ph. Explore our commitment to environmental, social, and corporate governance and discover how we are making an impact. The fumarate moiety of Alubra increases its melting temperature, which allows for greater functionality at high press speeds while the stearate chain maintains the lubricity of the compound and supports low ejection forces. Standard, 29 CFR 1910.1200 and Canada's Workplace Hazardous Materials Information System (WHMIS . Microcrystalline cellulose is produced by subjecting to a high shear treatment, at elevated temperature and pressure, a reaction mixture of a cellulose material, an active oxygen compound and water, for a time effective to depolymerize the cellulose material. 4 0 obj zW0} kAmS AYiy QJVWwi ED`52u-I~_ViT3+3kIT D2/A5vP5MHt(*vCBZ5UALFS0Mr v6t3dDda!03O$V>S6n| 3Fz. It is insoluble in water, dilute acids, common organic solvents and oils, partially soluble with . We can send by Fedex, by ship or by plane according to international rules. /Group << /S /Transparency /CS /DeviceRGB /I false /K false >> MSDS Ref. Microcrystalline cellulose (MCC) for industrial purposes is usually obtained from wood pulp and purified cotton linters. Avicel Microcrystalline cellulose is manufactured in the United States of America by Dupont. stream PDF (28.38 mb) 2022 Corporate Fact Sheet. Packaging: 34 x 50 kgs fiber drums. This Microcrystalline Cellulose . <> No. It is made from purified partially depolymerised Alfa cellulose relatively free from both organic and inorganic contaminants. << AFFINISOL HPMC has been specifically designed for generating solid dispersions via spray-drying (SDD) or hot melt extrusion (HME) in the pharmaceutical industry. Same quality to grades 102/90M, but very low moisture content (< 1.5 %) for processing water-sensitive actives. More than 65 years later, Avicel continues to command global acceptance, with no signs of its popularity waning. 51395-75-6 Avicel RC 591. Within the pharmaceuticals field, where the bulk of this material is utilised, Avicel Microcrystalline cellulose functions as a filler and diluent, dry binder, flow, disintegrating, and compression aid in tablets, capsules, and granules. II: effects of changes in the content of Microcrystalline Cellulose, AAPS PharmSci, 2 (2000) 45. The chemical structure of cellulose is shown below: In the biosynthesis of cellulose, two molecules of -D-glucose molecules combine via a condensation reaction (elimination of one molecule of water) to form the so-called cellobiose unit. The product would later go on to be commercialized under the brand name Avicel by FMC Corporation. Its used in capsules and tablets, both in wet granulation and direct compression processes, where it serves as a moisture adsorbent, tablet, and capsule diluent, and tablet disintegrant.It is also widely used as a supplementary formulation aid, primarily to enhance the . Avicel PC 611 (FMC Biopolymer) . Some substance identifiers may have been claimed confidential, or may . Material safety data sheet - FMC Corporation. SUBSTANCE IDENTIFICATION 1.1. Ui[(lY[|//o)ZmqbQT-Y.M|se[)m?(WRV.W8J/j}9>X.VNsZNOp'^14nuXM%rea5]@ MKnNe 2021 Annual Report. We are the leading manufacturer of Microcrystalline Cellulose coated with - RC 581 Grade in the industry. iQuLyI4D@yq#u0dZt=0?QUz{K6by_C"vW~Nj$bo? pb7c8BHqCRX_eL +90w~ gk[YBkf9eDNJdNn q^16mi=4Sr0~{lZ>yvMqS'e,MqB?;Oy9s'$8asJgEh0SS>|J58ub^q c Dh)#t'kTfIZT1-_y"+wXj,qo!~ozc}ZemZ``$'vj{, Ga;]2iY*DIh~F3Z!.pkL:bHHBTbIcw9.Xo$4,?On4s=R,KLz /M|#PF(j%j oF2[5 ,rx)bd1$LM4Dc-d\@W D?A?L/7>s]-};Z if^+e3}AeQ# U%l3K?WW$iJ:tSS8M /&N2R3d2Nl2u]qg*WVkq2lhJZIiE++nKfq)sO~z(d| 7u4w!o}::#l}tEw'M}BEntaugq**t|KZUTe-1J+|. Go to Investor Relations. AFFINISOL HPMC HME offers hot melt extrusion process flexibility in choosing a polymer viscosity that optimizes drug release profiles and against the factors affecting solubility. cas:9032-51-3 msds CELLULOSE PAB. PDF (4.11 mb) Footer menu 1. This grade of polymer film remains intact at pH< 6, thus protecting the API in gastric environments. INCI. Co-processed excipients deliver functional synergies to address formulation challenges with simplified, single ingredient solutions. . Revision No. As one of the most robust and efficient excipients, it tolerates high salt content, high temperature and is stable in a wide pH range. Microcrystalline Cellulose. Unique functionality for a broad range of pharmaceutical applications. pfTr^i5wOg)y .6 68ZWN hZB{u7ps@uWm 2#@+o/Z {vd^qHe42)Xz[T|[6:q/ i0lGX*}L[7;SGS "lj@::4G[IN{ } !1AQa"q2#BR$3br It is a white, free-flowing powder. SDS - Safety Data Sheet. Product and Company Identification . . Avicel CL-611 Microcrystalline Cellulose and Sodium Carboxymethylcellulose Manufacturer FMC Corporation Product code 103-B Revision date 2014 September 30 Language English. Interestingly, the discovery of Avicel was accidental, the team was attempting to break up hydrolysed cellulose using a Waring Blender. Biologicals by FMC. % Microcrystalline Cellulose (MCC) MSDS 1. stream common form is used in vitamin supplements or tablets. cas:9004-36-8 msds CELLULOSE ACETATE BUTYRATE. Researcher's newest research report, the "Wood Pulp Based Microcrystalline Cellulose Industry Forecast" looks at past sales and reviews total world Wood Pulp Based Microcrystalline Cellulose sales in 2022, providing a comprehensive analysis by region and market sector of . This is unlikely to be a problem when Microcrystalline cellulose is consumed as part of a medical product where it is used as an excipient in the formulation. : 160182. Chemically, it is an inert substance, is not degraded during digestion and has no appreciable absorption. The current product range and recommended usage are summarised below: Microcrystalline Cellulose is currently listed in the United States Pharmacopoeia and National Formulary, the European Pharmacopeia, the Japanese Pharmacopoeia, the British Pharmacopoeia, in addition to the Indian and Chinese Pharmacopeia, to name but a few. Manufacturer: FMC BioPolymer. It is also used in plaque assays for counting. Are you sure you want to delete your template? PDF (2.77 mb) 2021 FMC Sustainability Report. Foam Booster/Stabilizer; Rheology Modifier; Stabilizer-Emulsion; Suspending Agent . Synergies to simplify formulation challenges and reduce operational costs. It can be processed both via wet granulation and direct compression, as well as roller compression and extrusion-spheronisation. lH5JWy}DgKRR"Fs 1. By utilizing proprietary co-processing technologies, Dupont also manufactures LATTICE NTC products. ETHOCEL premium ethylcellulose resins are water-insoluble polymers. %&'()*456789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz Microcrystalline Cellulose / Avicel PH-102. The polymers added organosolubility further creates advantages for employing HPMC in solvent spray-drying applications. In Cellulose and Cellulose Derivatives in the Food Industry, T. Wstenberg (Ed. Chemsrc provides Cellulose microcrystalline(CAS#:9004-34-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. \C[i+rY2$V,,WT#_)3K?=/fW%[,lE"V?C PipEAz_xO;`cZsC0qcx;@tp]c*T7ge @Mty?]@SNmpf/]q#I,G1I?SR.@z*Xb KjR hb{T$CQrr Yx%O@~57eL5S\r-|EZ)Y.C]KuIlW]@12KY,S]C"e%b*|YX122igjl; @! ,}b;XQ})+l{~d_=sUtl V"CbKas+;fc>]bt#F,Md]]!5xae ;}rr^NI]rUc^,5Lc(fyyp*a=~U}WveuTLYX/ _V{#* g(*Rrm0gyv9i@0UT:A+{eW/y BS3_!Qv rt^BN! No. : 5. With an account you can check out faster, view your online order history and access your shopping bag or saved items from any device. %PDF-1.4 Examination of urine, blood and faecal levels of vitamin B 1 during microcrystalline cellulose ingestion showed no difference from control periods (Anonymous, 1966). Material Safety Data Sheet or SDS for Microcrystalline cellulose 9004-34-6 from chemicalbook for download or viewing in the browser. Microcrystalline cellulose is an exceptional material and one of the most widely used excipients in the pharmaceutical field. Microcrystalline Cellulose E460 MSDS 1. microcrystalline cellulose and carboxymethylcellulose sodium NF, Ph. q9;v80q>jZ w !1AQaq"2B #3Rbr All Rights Reserved. stream /Type/Page /PRNewswire/ -- ReportsnReports added Global Microcrystalline Cellulose (MCC) Market Growth 2019-2024 to its online research database. MATERIAL SAFETY DATA SHEET. This paper is based on a study of the interactions that take place during the process of hydrogel formation, break down, and recovery. Avicel is one of the best-known pharmaceutical excipient brands and, without doubt, one of the most frequently used raw materials in solid oral product formulation and manufacture. Pharmacel 112 can be used in a wide range of oral solid dosage (OSD) forms as binder, compressing agent . Remove These include amphiphilicity, a higher degree of crystallinity, surface area, higher hydration properties, and morphology. }o]X4]. As some of the data above show, microcrystalline cellulose possesses unique physicochemical properties that set it apart from native cellulose. Product Name Cellulose microcrystalline. HAZARDS IDENTIFICATION EMERGENCY TELEPHONE NUMBERS (302) 451-0100 (FMC Plant - Newark, Delaware) (303) 595-9048 (Medical - U.S. - Call Collect) For leak, fire, spill, or accident emergencies, call: (800) 424-9300 (CHEMTREC - U.S.A. & Canada) (703) 527-3887 (CHEMTREC - Collect - All Other Countries) EMERGENCY OVERVIEW: Off-white, free-flowing, odorless powder. There have always been two different points of view for the liquidity of MCC. LATTICE Microcrystalline Cellulose has many important uses within the food, pharma, specialty applications and industrial such as non-stick coatings, insulation of wiring, crop protection and paints,coats and inks. Avicel RC-591 offers ideal thixotropic bahavior for stabilizing suspensions while Avicel CL-611 is a stabilizer for reconstitutable or dry suspension formulations. Production of Pharmaceutical Grade Microcrystalline Cellulose. Carrageenan is a naturally occurring family of hydrophilic polysaccharides extracted from several closely related species of red seaweeds. Upon ingestion, microcrystalline cellulose is not absorbed into the blood stream and therefore has little toxicological potential. q86@on$^X_HuH;3` No. There may be more fiber in your food than you realized. $4%&'()*56789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz ? It is hygroscopic and insoluble in water. CAS 9004-34-6, pH 5 - 7.5. Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents. Hi, let us know if you have any questions as you visit our website. Eur., JPE . Earth Supplied Products LLC. This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication. CAS #: 9004-34-6 . Description: Microcrystalline Cellulose is a term for refined wood pulp manufactured through plant fibre hydrolysis. Avicel co-processed products are high functionality excipients offering improved powder flow, granule properties, tablet compression, and mouth feel. *r_ *?~4$ &0Y# GRINDSTED Xanthan Gum is a naturally fermented product of carbohydrates and is applied in various liquid, semi-solid and solid pharmaceutical dosage forms. vdZ@Rgl{eU+7N!3!|hUmW)~}U*7k i@j)q["MEydtP"ftFu]t }JN~A"8lz7#}J.i@ qaj/QU<5OrVMfl{pL? Dupont acquired the microcrystalline cellulose business of FMC Corporation in 2017. Microcrystalline Cellulose; Cellulose; Functions. Note that Avicel Microcrystalline cellulose is available in different particle sizes and moisture grades that have different properties and applications. The table below shows the most common physicochemical parameters of this raw material. It is, however, a good source of fibre. ). 130. < gV2@o2s&WS@Et%Up:`U '_ h?8qyP=&> GFprm9A!uu1 }&*kQ c^&eX}^K}h9YCb2L(yL):,+g8_u. In many applications, one METHOCEL product can perform the job of two, three or even more ingredients saving money and time. Aqueous suspensions of microcrystalline cellulose have . HMo@9, U Q!R/1*;` Alginates also function as actives in some anti-reflux products. Product Name: Microcrystalline Cellulose E460 1.2. A family of polysaccharide products that allow distinctive drug delivery solutions. Eur., JP Product Specifications: Chemical and Physical: Loss on drying 2.0 - 5.0 %* Bulk density 0.29 - 0.36 g/cc Identification A, B Passes Degree of polymerization NMT 350 units pH 5.5 - 7.0* Conductivity NMT 75 S/cm X]s ;/4'OslUK:|QY`IL|w @ I!*2T~IN?*}y2*49]yOQ*VG%Gu,;&9zE{q==xvrv}rd(yG*qN6E0K$IBWhe United Nations Sustainable Development Goals, Alginates Protanal, Manucol, Protacid and More, Barrier membrane, Controlled release hydrophilic matrix, Taste masking, Carrageenan Gelcarin, Viscarin and More, Controlled release hydrophilic matrix, Muco-adhesive, Rheology modifier, Rheology modifier/stabilizer, Thin films, Rheology modifier, Rheology modifier/stabilizer, Binder, Controlled release hydrophilic matrix, Rheology modifier, Rheology modifier/stabilizer, Shell - hard capsule, Tablet coatings, Thin films, Topical, Capsules, Other, Solutions, Suspensions, Tablets, Controlled release hydrophilic matrix, Hot melt extrusion, Muco-adhesive, Osmotic pump, Muco-adhesive, Rheology modifier, Rheology modifier/stabilizer, Thin films, Topical. FMC has deep roots in the food production system worldwide learn more about our latest advances in the future of agriculture. CAS #: 9004-34-6 1.6. Innovation is at the heart of IFFs purpose of applying science and creativity to create a better world. Doses up to 30 g per day appear to be . Avicel Microcrystalline cellulose is a type of cellulose, a naturally-occurring, large molecular weight polysaccharide found in woody plants. If you are already a ChemPoint customer then sign up for access to our online ordering website. Microcrystalline cellulose (MCC) is the most commonly used spheronizing aid in a formulation undergoing extrusion spheronization. Powder becomes slippery when wet. Combinations of microcrystalline cellulose (MCC) and sodium carboxymethyl cellulose (Na-CMC) are commonly used as stabilising agents and suspending agents in pharmaceutical formulations. Our customers around the world enjoy the benefits of TEXTURECEL NaCMC in various wound care products, too. GRINDSTED Xanthan Gum readily dissolves in water under ambient conditions without the need of special high-shear equipment. Ac-Di-Sol Croscarmellose Sodium is one of our flagship offerings for pharmaceutical manufacturers. . Avicel RC-591 & CL-611 - Description. Medium size standard MCC grade, suited for the majority of directly compressible actives. All Rights Reserved. It does not interfere with other nutrients when added to food products, and is instead, an excellent carrier and stabiliser, helping prolong the viability of food products. endobj undefined. };khd5x=fr X\o^ . GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA 1. Chemical Name Microcrystalline cellulose (INCI Name): MCC, cellulose gel Common Name Avicel PH105 Microcrystalline Cellulose CAS Number 9004-34-6 Impurities and/or Stabilizing Additives No data available Section 4: First Aid Measures General Advice No data available If Inhaled Remove person to fresh air. Gloves, eye protection and a dust mask should be used. Cellulose microcrystalline MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. These grades have particle sizes ranging from <30 to approximately 200. FMC Corporation 2929 Walnut Street Philadelphia, PA 19104 (215) 299-6000 (General Information) . However, it yields non-digestible fibre. Have an order or account question, find answers in our Online Support articles. Wu, K. Zuurman, H.W. JRS Pharma: PROSOLV SMCC 90 LM: Microcrystalline Cellulose, Colloidal Silicon . The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. This extends the funcionality of microcrystalline cellulose to meet specific viscosity, gelling, suspension and stabilizing properties ChemPoint is an approved supplier of LATTICE MCC in industrial applications, providing dedicated marketing, sales, order fulfillment, and technical support for customers in the EMEA region, Protect and improve AI potency, entrap oil droplets and improve stability, physical barrier that helps suspend particles and breaks down under shear and reforms quickly under rest. In roller compaction, Avicel Microcrystalline cellulose improves compaction during the ribbon phase, enabling a trouble-free process while also preserving the plasticity of the compacts. 1 0 obj <> (&E. The product range encompasses methylcellulose and hydroxypropyl methylcellulose (hypromellose) each available in different grades to address a wide range of applications including tablet coatings, granulation, controlled release, drug layering, vegetarian hard-shell capsules and amorphous drug stabilization. In summary, Avicel microcrystalline cellulose is virtually inert, its energy content is very low or zero and it is not absorbed. Find answers in our support articles. Buy Chemicals. Millipore. Product name: Microcrystalline cellulose; CBnumber: CB4217972; CAS: 9004-34-6; EINECS Number: 232-674-9; Synonyms: MICROCRYSTALLINE CELLULOSE,cellulose; pH 6.0 to 8.0 . Microcrystalline Cellulose NF. Explore how you can develop your career and bring your creative ideas to life at IFF. The charts below provide guidance on how to select and use standard and co-processed grades of Avicel Microcrystalline cellulose in pharmaceutical products. They are differentiated from each other by the amount of 3,6-anhydrogalactose as well as the number and position of ester sulfate groups present. ECOLOGICAL INFORMATION ECOTOXICITY Practically nontoxic to fish: Rainbow trout LC50 (96hr) > 100%, saturated solution (Microcrystalline cellulose, Avicel PH-101) PERSISTENCE AND BIODEGRADABILITY Inherently biodegradable. Battista, O. gwf;J(e0o|1p{R~P^);ao!%{0KD7. endobj Product Name: Microcrystalline Cellulose 1.2. Currently, it is marketed both directly and indirectly (through distributors) depending on the country in question. Studies from the World Health Organisation and the European Food Safety Agency have concluded that Microcrystalline cellulose has no safety concerns for the public when used in animal nutrition. EMCOCEL 90 M. 130. 6 0 obj Product Specifications: Chemical and Physical: Loss on drying, % NMT 6.0* Viscosity, cps, 1.2% solids, 120 sec 39 to 91 . PROSOLV SMCC, silicified microcrystalline cellulose, is a unique combination of microcrystalline cellulose (MCC) and colloidal silicon dioxide (CSD).A high functionality and multifunctional excipient, it requires less complex processing, has high inherent functionality, and passes that functionality on to the drug formulation. >z+{!A6wy @nLK3R#hRn sba3;b61V:#Z3X,*?RC!wPmqd7WkA'aZMt6PFV3SEvlY'=p.mn[I{puc\6'ZIyI%rD'zA!"t3I2F ^R;LK,?:&THv*y^K> o0Af?J9J-{s2&cCn)32ADzl%sS5O~J[ A schematic illustration of the manufacturing process for Avicel Microcrystalline cellulose is shown below. : 1. iq/iVO"5VI}dn.#q^(fJ),BN yb5*4reh1"!E?mR*%fK,e4?A\{OAXr1' tx&Ul{J,57n%PV E2eMS5'UOL wdD{s)4N-m ab K * ~CVHg}{J2.M}O)^}|Z{V+ >AW|? eqgP}OF'v7heLP&Y,eoo`x7lR}0iRVP],=`_2rS'*X$b)+XV2;fbQDgkgx:IZ|v>lDD/TDqz %RL CAS 9004-34-6. CAS #: 9004-34-6 The representative usage of Avicel PH-101 and Avicel PH-102 Microcrystalline cellulose in wet granulation and direct compression is shown in the following two examples. The application areas for Avicel Microcrystalline cellulose are immense and encompass many industrial sectors such as food, pharmaceuticals, and cosmetics. IFF has decades of experience controlling these naturally derived materials, which means you can count on consistent performance, every time. Learn about FMC's industry leading goal of net-zero emissions by 2035. Material Safety Data Sheet TALSTAR S INSECTICIDE Version 1 Page 1 / 8 SDS # : 6320-A This MSDS has been prepared to meet U.S. OSHA Hazard Communication Standard 29 CFR 1910.1200 and Canada's Workplace Hazardous Materials Information System (WHMIS) requirements. Request media, explore upcoming events and read our latest updates. SCMm_>x^O9l (n. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING Material Name: Estradiol Tablets Trade Name: RONFASE . cas:9000-11-7 msds Carboxymethyl cellulose. Generally, these can be classified into two broad groups: Standard grades, and Co-processed grades. Synonyms: Cellulose, Cellulose powder, Cotton linters. . Carboxymethyl Cellulose Sodium N/A Nutrition & Biosciences www.pharma.dupont.com HO 00017 - 0 E L 02.2020 www.dupontnutritionandbiosciences.com . Combines good flow and high compactibility. Fiber supplements can lessen the absorption of some . Low use levels of GRINDSTED Xanthan Gum are sufficient to provide desired viscosities and textures. Cellulose, microcrystalline | C14H26O11 | CID 14055602 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological . xv}O2' H~KEe9>G/,:9\i endobj ChemicalBook. endobj Htn@sHaYoEJ*H[G&o)o9;0s N'3[*%M]vAu#9Tqpg9D& The aqueous solution to barrier membrane coating. The METHOCEL Premium family of water-soluble polymers for pharmaceutical applications offers exceptional flexibility and a broad range of properties typically not found in other water-soluble polymers. MATERIAL SAFETY DATA SHEET Lattice NT Microcrystalline Cellulose MSDS Ref. : 9004-34-6 1.2 Relevant identified uses of the substance or mixture and uses advised against Copyright 2023 by International Flavors & Fragrances Inc. IFF is a Registered Trademark. A., and Smith, P. A. To help, weve put together a simple guide for selecting Avicel Microcrystalline cellulose grades, with simple explanations of some of the most common grades, plus recommendations that will serve the majority of buyers. if interested in purchasing or obtaining a sample for assessment, you should contact Dupont themselves directly. Avicel Microcrystalline Cellulose Physical Properties. % Patel, F. Podczeck, Investigation of the effect of type and source of Microcrystalline Cellulose on capsule filling, International Journal of Pharmaceutics, 128 (1996) 123-127. Learn about our new global sustainability platform, Learn about FMC's industry leading goal of net-zero emissions by 2035, Learn about FMC's differentiated biologically-based crop solutions. MATERIAL SAFETY DATA SHEET Version: 1.0 1. Comprecel MCC (Microcrystalline Cellulose) is a pharmaceutical excipient derived from nature's most abundant and renewable raw material-wood pulp. To overcome the pitfalls of known overlays, we tested suspensions of microcrystalline cellulose Avicel RC/CLtrade mark as overlay media in the plaque and plaque-inhibition assay of influenza viruses. . The table below lists the most important chemical identifiers applicable to Avicel Microcrystalline cellulose. Explore our end markets, products, ingredients and essential solutions or get in touch with us about your order. The process is relatively basic; and starts with treating cellulose, obtained as a high-grade pulp obtained from fibrous plant material, with mineral acids, followed by purification and spray-drying. METHOCEL cellulose ethers are water-soluble polymers derived from cellulose. MATERIAL SAFETY DATA SHEET. /Producer(Sub Systems, Inc.)/CreationDate(D:20211228124915+05'00')/ModDate(D:20211228124915+05'00')/Creator(Sub Systems, Inc.) Microcrystalline Cellulose Side Effects. <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 6 0 R/Group<>/Tabs/S>> Avicel co-processed grades are co-spray dried blends of Avicel microcrystalline cellulose with synergistic pharmaceutical excipients to yield functional benefits beyond simple physical blends. Watch Now. ( MATERIAL SAFETY DATA SHEET Product Name: MICROCRYSTALLINE CELLULOSE Date/ Revised: 27/November/2012 Page 4 of 4 15. <> IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1 Product identifiers Product name : Avicel PH-101 Product Number : 11365 Brand : Fluka CAS-No. Material Safety Data Sheet or SDS for Cellulose microcrystalline 102331 from Merck for download or viewing in the browser. The smallest units, the elementary fibrils (cellulose crystalline strands) are made up of many -(1-4) glucose chains which are bundled to form microfibrils.