Mike Hodges Football Coach, Karen Akhurst Funeral, Millburn Deli Sloppy Joe Recipe, Articles M

Increased sleepiness. "A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)". hyperthyroidism. The Remarkable Heart-Friendy Properties of Avocados. With the recent announcement by a National Cancer Institute commissioned expert panel that a variety of so-called 'indolent' neoplasms such as ductal carcinoma in situ (DCIS) and high-grade prostatic intraepithelial neoplasia (HGPIN), formerly understood to be forms of breast and prostate cancers, respectively, should be renamed to reflect their intrinsic benignity, a veritable sea change is occurring within the conventional medical establishment. Thanks, I am not suggesting I believe in all that I see. (31) 3351-3382 | 3351-3272 | 3351-3141 | 3351-3371. location of blind frog ranch associe-se. I discovered this article published in Wakeup World. Researchers are currently studying. Share your experience, learn from others. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' Marketed as superior to traditional glandular forms extracted from pigs (whose endocrine glands are far more bioidentical than any other animal we know of) due to the dose-to-dose standardization of the so-called 'active ingredient' T4 versus the natural variations in hormone concentrations found in the 'real thing,' which incidentally contains a wide range of additional hormones including T1, T2, T3, all of which are vitally important. In addition, untreated hypothyroidism is associated with a gradual decline in cognitive function and memory. You must log in or register to reply here. Most of the time, doctors tell patients treated with LT4 that any side effects will be temporary and almost ineluctable, and are usually dealt with through dose reduction. The article also stresses that too many people are being given the diagnosis of either hypo or hyperthyroidism. Millions of people who were not only wrongly diagnosed with cancers and subsequently aggressively treated for them with chemotherapy, radiation and surgery, are now being told that they would have been better left undiagnosed and untreated. Nope. Also this study finds no link with breast cancer, when others have found a link. 2013 May ;98(5):1982-90. Metab.87 (2): 48999. Whereas a patient who had suboptimal thyroid function, but did not have noticeable symptoms, is suddenly given pharmacological doses of synthetic T4 and suddenly experiences the wide range of acute, adverse health effects associated with a now hyperactive and/or increasingly disrupted thyroid, as a result. However, I do not believe it was out of the blue now. Just for entertainment value take a look at some more dodgy correlations : I rather liked the correlation between consumption of orange marmalade and birth rate - in the years after the second world war if I remember correctly. The first blood test typically done to diagnose hypothyroidism measures the level of thyroid-stimulating hormone (TSH) in the blood. A couple of caveats to note in this study: The authors found a statistical correlation between the increase in sales of the thyroid medicine Synthroid, and an increase in lung cancer in Italy. I hope that with increased knowledge we will all find the right road. Post author By ; Post date jaripeo hillsboro oregon 2021; what task do they have at camp westerbork on millions treated for hypothyroidism at risk for lung cancer on millions treated for hypothyroidism at risk for lung cancer Note: Only a member of this blog may post a comment. Reddit and its partners use cookies and similar technologies to provide you with a better experience. It took over five years before the someone figured out my ongoing symptoms were due to hypothyroidism. Asesora y Consultora Web3 para empresas. Levothyroxine is a widely prescribed medication for the treatment of an underactive thyroid. Tokushima J Exp Med 1991, 38:2535. [13] Hollowell JG, Staehling NW, Flanders WD. But what can be done for patients who are at low There are many links attached. hyperthyroidism. Monaldi Arch Chest Dis 2003, 59:140145. I have sent the link that I read today. This T4 blocking/endocrine-disrupting property of the synthetic form would also activate a negative feedback loop within the endocrine system, further suppressing remaining thyroid function, and resulting in the atrophy of the compromised thyroid, a iatrogenic 'self-fulfilling prophecy' if you will. A place for patients and relatives. There are several books out there written about the topic. [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: [I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. I have posted the link, so you can see if it has any merit. Oops, I just saw that I posted the same article. Data sources: The Medline and Cochrane Library electronic databases . Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional. Respiratory system Hypothyroidism weakens the respiratory muscles and decreases lung function. New Cholesterol Drug Guaranteed to Prematurely Kil Beware the Walgreens travel vaccination scam. Brit Med J 1978, 1:210212. Perhaps she and I could co-author? Salt, Sugar, Fat: 15 Shocking Facts From the Book Dear Doctor, Do You Really Know What Vaccines Cont Colloidal Gold: Discover the Benefits and Wonders, Scientists Explain Why HPV Vaccines Are Unsafe. However, that information will still be included in details such as numbers of replies. Angiology 2000, 51:S65S68. bear in the big blue house characters; colne times obituaries this week Menu Toggle. I will respond more later onBut I will briefly say I was on Synthyroid from 1993 to 2011. ", Cure Alveolar Soft Part Sarcoma International, COMPLETED - Dana Farber Vaccine Clinical Trial (GVAX), Axitinib and Pembrolizumab (Keytruda) in Miami, US, TECENTRIQ (atezolizumab) by Genentech, Treatment of Non-Resectable Primary Tumor, Immune checkpoint inhibitors ICI (PD-1 and PD-L1 targeting drugs), Toxicity, problems and potentiation strategies, Treatment response criteria and evaluation/scanning problems/rare cases, treatment discontinuation/re-treatment, Side effects/complications of the local ablations, High intensity focused ultrasound (HIFU), Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer, http://www.greenmedinfo.com/blog/study- ng-cancers. If you are already a member, please, Levothyroxine and lung cancer in females: the importance of oxidative stress, recent announcement by a National Cancer Institute, T-score based definition of osteoporosis and osteopenia, 30-billion dollar a year market in statin drugs. Oops I have just bought my first jar of marmalade in over ten years! They then correlated drug sales with cancers, eliminating the contribution of age and smoking for lung cancer risk. Correlation is NOT causation. PLoSone 2011, 11:e27547. Nanosized aluminum being sprayed in the atmosphere CDC Admits as Many as 30 Million Americans Could b Why Turmeric May Be the Diseased Liver's Best Friend. I have so much to say about this I could write a book. Another recently approved drug is tepotinib (Tepmetko). Article published in Wakeup-World.Com. They found no significant correlation between T4 sales and breast, colorectal and gastriccancers, but did find a significant correlation for lung cancer (p < 0.05) corrected forsmoking and age. I have always found this condition a riddle. The study looked at the prevalence of breast, colorectal, gastric and lung cancer in 18 Italian Regions during 2010 and correlated this data with sales of LT4 in 2009, focusing on women aged 30-84. Levothyroxine therapy and serum free thyroxine and free triiodothyronine concentrations. One of the main drawbacks of administering T4 in isolation is the possibility that it will not convert adequately to T3, and will therefore back up causing excessive T4 activity, i.e. The estimated 2.3 million new cases indicate that 1 in every 8 cancers diagnosed in . The increasingly global medical-industrial complex has begun to co-opt all aspects of the natural human bodily life cycle, and all the organ systems within it, as potential targets of medical surveillance and intervention, not excluding the human thyroid. Eventually, the decline in thyroid hormone production can result in any of the following: Fatigue and sluggishness. Other factors that can trigger thyroid problems include: autoimmune diseases like Hashimoto's or Graves' disease; thyroid surgery; radiation treatments to the neck or upper chest; and certain medications, including interferon alpha and interleukin-2 cancer medications, amiodarone . This website is for information purposes only. Is that what releases free radicals? Keep checking back for the register link to appear. JavaScript is disabled. Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. It is worth reading. I do not believe in random events, of nature or otherwise. Compared to patients without hypothyroidism, those with a high TSH level before hospitalization stayed in the hospital 1.2 days longer and had a 49% higher risk of 30-day readmission and a 43% . Endocrinology 1985, 117:12011208. At GreenMedInfo.com, we have indexed plenty of peer-reviewed research on over 30 natural substances, including nutrients and minerals, which may help to resolve low thyroid function, and conversely, over 30 unnatural substances, e.g. The reality is that most cases of hypothyroidism today are diagnosed in populations who are experiencing a combination of basic nutritional deficiencies and chemical exposures, or who are simply going through a temporary down-cycle in thyroid function following a natural change, such as the natural postpartum drop that occurs in women after giving birth. [5]Wawrzynska L, Sakowicz A, Rudzinski P, Langfort R, Kurzyna M: The conversion to triiodothyronine in the lung: comparison of activity of type I iodotironine 5 deiodinase in lung cancer with peripheral lung tissues. As I have lung cancer and just recently was diagnosed hypothyroidI am very interested as to what you have to say about this connection.your personal insight and any books, websites would be appreciated.you may email me if you prefer. This relatively symptom-free reservoir of hypothyroid cases provides a veritable gold mine of potential office visits, billable services and drug prescriptions. The Flu Propaganda Matrix Continues To Promote Fea B Vitamins Slow Alzheimer's and Grey Matter Loss. Sayer Ji is the founder ofGreenmedinfo.com, a reviewer at theInternational Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of theNational Health Federation, and SteeringCommittee Memberof the Global Non-GMO Foundation. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.'. If You Don't Want Older Bones, Don't Be Low In Vit Background Mortality Rate for Vaccines, or Pseudo Everything You Ever Wanted to Know About Black Seeds. [2], The observation that patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. The omnipresent environmental contaminant perchlorate, an ingredient in jet fuel, is also a primary cause of hypothyroidism, but is almost never tested for by the conventional endocrinologists in their patient evaluations. Baked or Fried avocado fries [Vegetarian]. En 3 minutos recibirs en tu email COMPLETAMENTE GRATIS todo lo que necesitas para aumentar las ventas de tu empresa. [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. The authors of the study pointed out that levothyroxine (T4) treatment can lead to medication-induced (iatrogenic) thyroid over-activity (hyperthyroidism) and oxidative stress that can lead to a significant patient discomfort. [7] Kinoshita S, Sone S, Yamashita T, Tsubura E, Ogura T: Effects of experimental hyperand hypothyroidism on natural defense activities against Lewis lung carcinoma and its spontaneous pulmonary metastases in C57BL/6 mice. Hypothyroidism reduces respiratory drive and can cause obstructive sleep apnea or pleural effusion, while hyperthyroidism increases respiratory drive and can cause dyspnea on exertion. They then correlated drug sales with cancers, eliminating the contribution of age and smoking for lung cancer risk. Join the Patient & Caregiver Network. As I am the caregiver for my dad who has Stage IV lung Cancer, I hope more research can be done on this topic soon. 2002 Feb ;25(2):106-9. elevated TSH, without actually improving the overall physiological situation, nor the patients subjective experience of well being. undefined will no longer be visible to you including posts, replies, and photos. [5] Wawrzynska L, Sakowicz A, Rudzinski P, Langfort R, Kurzyna M: The conversion to triiodothyronine in the lung: comparison of activity of type I iodotironine 5' deiodinase in lung cancer with peripheral lung tissues. [9] Otto T, Fandrey J: Thyroid hormone induces hypoxia-inducible factor 1 gene expression through thyroid hormone receptor /retinoid x receptor -dependent activation of hepatic leukemia factor. Link posted. It may not display this or other websites correctly. Hypothyroidism can also lead to swelling of the tongue, hoarse voice, and sleep apnea. ", That study is like a fishing expedition. This is a horrible disease that ravages the body. Physician/Author on Facebook. [9] [10] [11] Although we should never forget that LT4 is a life-saving thyroid hormone replacement, and that one should not exclude that the pathological reason that leads to the prescription of LT4 could favor the lung cancer development also. [3], An old clinical observation on the relationship between lung cancer and thyroid function reported that patients were characterized by a low concentration of T3 and an increased T4/T3 ratio due to a decrease of 5'-monodeiodination (DI). 16.6k members in the AlternativeHealth community. To investigate the magnitude of the possible association between levothyroxine use and cancer risk, this retrospective c There is also compelling research indicating that desiccated thyroid extract (Armour thyroid) results in superior clinical outcomes versus the synthetic hormone, especially as concerns improved body weight. Hypothyroidism can cause depression and, without treatment, the symptoms intensify and directly affect the mental state. It looks at correlations, as if they had any merit on their own. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Thank you for bringing it to our attention. It's usually based on the results of blood tests. I read somewhere about the work done many years ago which was mistakenly read and accepted 28 y/o F Low levels across the board for TSH, T3, and T4, Acid reflux drug linked to more than doubled risk of stomach cancer study, thyroiduk.org - further-reading - thyroid-diagnosis-and-treatment. The increasingly global medical-industrial complex has begun to co-opt all aspects of the natural human bodily life cycle, and all the organ systems within it, as potential targets of medical surveillance and intervention, not excluding the human thyroid. They found no significant correlation between T4 sales and breast, colorectal and gastric cancers, but did find a significant correlation for lung cancer (p < 0.05) corrected for smoking and age. There is evidence T4 makes cancer more agressive, so although it increases the risk of cancer the mortality risk is higher. LifeGivingStore.comRed Light Therapy - Hydrogen Water Generators - Cascara Sagrada - Vitamins, Minerals & Amino Acid Supplements - Cocoa Products - Handcrafted Soaps - Grass Fed Organs & Glandulars - Nano Soma. Whereas a patient who had suboptimal thyroid function, but did not have noticeable symptoms, is suddenly given pharmacological doses of synthetic T4 and suddenly experiences the wide range of acute, adverse health effects associated with a now hyperactive and/or increasingly disrupted thyroid, as a result. Most of the time, doctors tell patients treated with LT4 that any side effects will be temporary and almost ineluctable, and are usually dealt with through dose reduction. Currently, the best practical approach is to base treatment decisions on the degree of TSH elevation, thyroid autoimmunity, and associated comorbidities. Millions of people who were not only wrongly diagnosed with 'cancers' and subsequently aggressively treated for them with chemotherapy, radiation and surgery, are now being told that they would have been better left undiagnosed and untreated. Even acute bouts of stress and subclinical adrenal insufficiency can cause cyclical downshifts in thyroid function. In 2011 I switched docs and was put on Armour as he told me Synthroid and the like are poison and they do not work. "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)", International Journal of Human Nutrition and Functional Medicine, Osteoporosis Is Scurvy of the Bone, Not Calcium Deficiency, 6 Bodily Tissues That Can Be Regenerated Through Nutrition, 7 Simple Ways to Unclog Your Arteries Naturally, Herbal Cream Clears 87.7% of HPV Cases Naturally, How WHOLE Turmeric Heals the Damaged Brain. Or, simply look at what the young-adult, T-score based definition of osteoporosis and osteopenia has done to convert millions of healthy middle-age and older women into drug-treatable patients, or, what the lipid hypothesis of cardiovascular disease causation has done to create a 30-billion dollar a year market in statin drugs, to fully appreciate the harms of overdiagnosis and overtreatment. Unfortunately, it's quite typical. I think part of sharing information here on Inspire is the discussions about the articles we share. Endocrinology 2008, 149:22412250. [1] Hercbergs AH, Ashur-Fabian O, Garfield D: Thyroid hormone and cancer: clinical studies of hypothyroidism in oncology. Hashimoto's disease progresses slowly over the years. Modern Medicine, Part I: How Healing Illness Becam Is your body getting too acidic? However, I'm learning from science writer friends, researchers, and medical professionals that (1) some studies are better designed and carried out than others, and (2) some journalists are more careful about drawing conclusions and writing sensational headlines than others. Endocrinol. Very interesting article, thank you for sharing. J Clin Endocrinol Metab. millions treated for hypothyroidism at risk for lung cancer. ", Orsomeone posts something about, say a diet or supplement and them some people think they are something it "Cures lung cancer.". If the results show that TSH is high and T-4 is low, then the diagnosis . This article is copyrighted by GreenMedInfo LLC, 2013, Some features are currently member only features. At GreenMedInfo.com, we have indexed plenty of peer-reviewed research on over 30 natural substances, including nutrients and minerals, which may help to resolve low thyroid function, and conversely, over 30 unnatural substances, e.g. Tokushima J Exp Med 1991, 38:2535. 'A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low . Breast cancer has surpassed lung cancer as the most commonly diagnosed cancer worldwide, according to GLOBOCAN. J. Clin. [7] Kinoshita S, Sone S, Yamashita T, Tsubura E, Ogura T: Effects of experimental hyperand hypothyroidism on natural defense activities against Lewis lung carcinoma and its spontaneous pulmonary metastases in C57BL/6 mice. The aim of the study was to assess the occurrence and nature of immune-related endocrine adverse events (irAEs) among patients with non-small-cell lung cancer (NSCLC) treated with nivolumab. In the U.S., the overall five-year survival rate for patients diagnosed with lung cancer is 25%, which is a 21% improvement over the . According to data from the National Health and Nutrition Examination Survey, years 1988-1994, [13] while 0.3% of the American population exhibits overt symptoms of hypothyroidism, 14 times more (4.3%) have so-called 'subclinical' hypothyroidism only detected via blood work. They compared sale of, "However, the impression we get from our experience, Health, Studies, Supps & Pharmaceuticals. I can understand why tennis 123 wrote, "I have so much to say about this I could write a book". May be of interest: Study: Millions Treated for Hypothyroidism At Risk for, Non-small cell lung cancer - Adenocarcinoma, Non-small cell lung cancer - Squamous cell, Top 5 Questions to Ask Your Lung Cancer Doctor, Patient & Caregiver Network Member Resources, Not A Member Yet? PMID 11836274. They only reappear when I need to fine tune the medication. Compression of the trachea, which may be positional, can occur with nodular goiters and thyroid cancer, and the latter can metastasize to the lungs. An Italian study published in the journalReproductive Biology and Endocrinology,titled Levothyroxine and lung cancer in females: the importance of oxidative stress, has raised a concerning possibility: levothyroxine (T4), one of the worlds most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). Join the forum, it's quick and easy . Results indicate that treatment with levothyroxine was linked with significantly increased mortality (hazard ratio = 1.19). weight loss, anorexia) was made many years ago together with an over production of both T4 and T3. arizona lockdown status today; tiktok unblocked from school; samantha and savannah concepcion Or, simply look at what the young-adult,T-score based definition of osteoporosis and osteopeniahas done to convert millions of healthy middle-age and older women into drug-treatable patients, or, what the lipid hypothesis of cardiovascular disease causation has done to create a 30-billion dollar a year market in statin drugs, to fully appreciate the harms of overdiagnosis and overtreatment. All the more reason to prescribe T3, I say! This relatively symptom-free reservoir of 'hypothyroid' cases provides a veritable gold mine of potential office visits, billable services and drug prescriptions. [4], DI activity in lung cancer was found to be lower than in peripheral lung tissue.[5]. Epub 2013 Mar 28. Privacy Policy. Study: Millions Treated for Hypothyroidism At Risk of Lung Cancer. Sin un requerimiento, el cumplimiento voluntario por parte de tu Proveedor de servicios de Internet, o los registros adicionales de un tercero, la informacin almacenada o recuperada slo para este propsito no se puede utilizar para identificarte. In fact, a 2004 study in subjects with normal thyroid function found that administration of tyrosine leads to a significant reduction in serum TSH and improvement in mood in winter compared with placebo, while the combined synthetic T4-T3 supplement leads to a worsening of mood in summer and no improvement in winter, indicating supporting glandular function is superior to 'replacement' therapy, as well as the role seasonality may play in hormone function and hormone treatment interventions. MASA Traditional Tortilla Chips by Ancient Crunch, Vitamins, Minerals & Amino Acid Supplements, http://www.greenmedinfo.com/blog/study- ng-cancers, Patients' Perspectives On Refusing Diagnosis Or Treatment For Lung Cancer, Unintended Weight Loss Is The 2nd Highest Risk Factor For Certain Cancers, Stress Causes Genetic Mutations; Cancer Thrives Under Stress, Tetracyclines (and A Few Other Antibiotics) As A Cure For Cancer, Vitamin B May Increase Risk Of Lung Cancer In Men, Study Says, Biggest Study So Far Shows Aspirin Reduces Any Cancer Risk, Methylation Levels Can Predict Breast Cancer Risk, Vitamin A As A Powerful Treatment For Cancer, Screening For Testicular Cancer (a Review), For Many Cancers Early Diagnosis Can Actually Be Deadly, As Altitude Rises, Lung Cancer Rates Fall, The Anti Depression Pills that may Kill Cancer, Holy Grail Blood Test May Detect Cancer Before Tumors Form. Once I got on the medication, the symptoms disappeared. Thus, I am monitored carefully. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.'. Ultimately, this Italian study brings further attention to one of a wide range of unintended, adverse health effects associated with the overdiagnosis and subsequent overtreatment of hypothyroidism, and the underlying failure of the conventional, largely drug-based paradigm to comprehend the causes and real solutions of disease and human suffering. A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low thyroid function (hypothyroidism). [15] Thanh D Hoang, Cara H Olsen, Vinh Q Mai, Patrick W Clyde, Mohamed K M Shakir. When a high-risk patient presents with one or more lung nodules, the path ahead and next steps seems obvious. Or, if fluoride, mercury, or any number of xenobiotic chemicals in the environment requiring selenium-dependent glutathione-mediated detoxification is causing the "low thyroid," why call chemical poisoning "hypothyroidism"? The Goji Berry: The Jolly Super Food That Gives Yo How to Prevent and Treat Insect Bites Without Hars Supreme Court Rules Drug Companies Exempt From Law Spain Study Confirms Hemp Oil Cures Cancer without Wheatgrass Turns Gray Hair Back to Its Natural Color, Medicinal Cannabis Used To Prevent Cancer Growth. Ultimately, this latest Italian study is bringing to our attention one of what is likely a wide range of unintended, adverse health effects associated with the overdiagnosis and subsequent overtreatment of hypothyroidism, and the underlying failure of the conventional, largely drug-based paradigm to comprehend the causes and real solutions of disease and human suffering. [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: "[I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. Those with the greatest risk of developing thyroid disorders are women who have a family history of the disease. So I will leave it as a simple thank you for passing this along. I don't believe there are thousands of people on to high a dose of t4, so why does it feel they are hyper? Methods: The study group included 35 patients (15 women, 20 men, 65.8 7.1 years) with NSCLC in stage IIIB (n = 16, 45.7%) and IV (n = 19,54.3%) who were treated with nivolumab.